Mark Orion provides this advice in his article on Ezine (wow, the second Ezine artile I've quoted this week). It's very, very important to note that when Mark talks about risk, he's talking about money.
I totally see where Mark is coming from and in the context of money, I agree. It's almost free to podcast so why not give it a whirl? If it fails you've lost virtually nothing.
There are other types of failure, however. Saying the wrong thing, coming across as an infomercial, producing a podcast that sounds bad or contains no real information are all things that will cause a business podcast to fail and not be as easy to recover from. Crediblity, unlike money, cannot be replaced over night.
I would change it to "Rick Big and Fail Often. Just not with your credibility"
Edit: Sorry, I lost the link somewhere...