Jill Hart has an article on Web Helper Now about the consideration of podcasting for home-based businesses. I can honestly say that I have never thought of using podcasting in that way.
When I think of home-based businesses, visions of Amway come too mind. That's not fair, though, because there are lots of home-based businesses that have nothing to do with soap. I primarily write for a living these days so other than the odd trip to work in a coffee shop for the day, my business is home based as well.
You'll have to hit the site for the details, but the highlights of the potential positives are:
Reach your niche market
Share your passion
Become an "expert" in your field
It's easy (I'm not too sure about this one!)